An Overview of the Package Insert and Contraindications of Filler Products in Korea / 대한피부과학회지

Filler injection is an extremely popular cosmetic procedure in Korea, but surprisingly few dermatologists are aware of the package inserts in filler products. In the era of legal dispute, it is important that we fully understand the indications, contraindications, and side effects of the individual filler products. The purpose of this paper is to provide a general overview of the contents of package inserts of filler products that are commercially available in Korea, especially in terms of the contraindications of filler injection. The authors emphasize that greater improvement in the Korean package inserts of filler products can be expected. Currently, practicing physicians are usually blamed for filler complications. We also found many significant translational errors. We hope that dermatologists take more interest in filler package inserts by reading this overview.

A Case of Intradermal Nevus Combined with Epidermal Cyst / 대한피부과학회지

The combination of an intradermal nevus with epidermal cyst or other adnexal tumors has often been described since 1952. Most of these reports have involved the coexistence of common epidermal cysts and melanocytic nevi. Herein, we report a 21-year-old Korean male, who initially presented to our department with a rapidly enlarging preexisting nevus on his back. The mass was surgically excised and histopathologically showed intradermal nevus combined with epidermal cyst.

Quality of Life of Acne Patients / 대한피부과학회지

BACKGROUND: Although acne is extremely prevalent, few studies have focused on what the patient with acne vulgaris experiences. Furthermore, despite recent advances in the accurate measurement of health outcomes, few studies have discussed the influence of acne on discrete aspects of patients' experiences such as their quality of life. OBJECT: To determine the influence of acne vulgaris on the quality of life of adult dermatology outpatients, we performed cross-sectional and longitudinal questionnaire study. METHOD: Sixty patients with acne vulgaris attending appointments with their dermatologists. Findings using Skindex, a validated 29-item instrument to measure the effects of skin disease on patients' quality of life. Results are reported as 3 scale scores (functioning, emotions, and symptoms) and a composite score (average scale score). In addition, dermatologists rated the clinical severity of patients' skin disease. Higher Skindex scores indicate greater effects on quality of life. RESULTS: Patients with acne experienced functioning and emotional effects from their skin disease comparable with those of patients with psoriasis, but experienced fewer symptoms (for patients with acne and psoriasis, respectively, Skindex functioning scores of 14.9 and 22.8 [p=0.08]; emotion scores, 39.2 and 38.9 [p=0.95]; and symptoms scores, 29.5 and 42.1 [p<0.05]). Skindex scores were higher in older patients than in younger patients, and patients aged 40 years or older were less likely to report improvement in their acne after 3 months (43% vs 85%; p<0.05). Among patients reporting no improvement in their acne, older patients reported greater effects of their acne on their quality of life. Furthermore, in multivariate analyses, older adults reported more effects of acne on their quality of life than younger adults, even after controlling for sex and acne severity as judged by the dermatologist. CONCLUSIONS: Acne vulgaris significantly affects patients' quality of life. Sex, age, severity of acne and duration of acne can effect on quality of life of acne patients.

The Korean Version of Skindex-29 / 대한피부과학회지

BACKGROUND: Most available dermatologic quality-of-life measures were written in English. So these must be translated for use in Korea. Our purpose was to translate and adapt culturally into Korean a skin-related quality-of-life measure Skindex-29, and to begin preliminary assessments of its reliability and validity. METHODS: Cross-cultural adaptation questionnaire studies were performed. Two hundred and sixty adult outpatients and healthy people responded to the Korean version of Skindex-29. Evaluations of the semantic equivalence of back-translated items, reliability, construct validity, and content validity of the Korean version were the main outcome measures. Comparison between the Korean version and other versions of Skindex-29 (Spanish and American) responses was also performed. RESULTS: Five problematic items required a second translation and back-translation to achieve satisfactory agreement with the original instrument. The final Korean version of Skindex-29 was internally reliable. The instrument demonstrated both construct and content validity. As hypothesized, scores for dermatologic patients were higher than those of healthy persons and scores for patients with inflammatory diseases were higher than those of persons with isolated skin lesions. Skindex scale scores of the Korean version and other versions of Skindex-29 were similar. CONCLUSIONS: We have developed a semantically equivalent translation of Skindex-29 in Korean. Our preliminary evaluation of its measurement properties suggests that it is a reliable and valid measure of the effects of skin disease on the quality of life in Korean patients.

Superficial Cryotherapy of Alopecia Areata in Eyebrows / 대한피부과학회지

Alopecia areata is a common skin disease with diverse modalities of therapy. The eyebrows are one of the target sites of alopecia areata and may be the only affected site. We report our recent experiences of superficial cryotherapy with liquid nitrogen to promote eyebrow hair growth due to alopecia areata. According to our results, superficial cryotherapy of alopecia areata in eyebrows can be an effective mode of treatment.

Thoracocervicofacial Purpura Occurred After Epileptic Seizure / 대한피부과학회지

The thoracocervicofacial pupura is an obstructive pupura, which occurs in the various conditions with elevated pressure in the thoracic cavity. This pupura can occur as an unusual consequence of epileptic seizure. A 28-year-old man visited due to the syncope and the thoracocervicofacial pupura. His creatine kinase level was elevated. Therefore the cutaneous manifestation is thought to be due to epileptic seizure. Here we report a case of thoracocervicofacial pupura as the unique manifestation of epileptic seizure.

A Case of Trichilemmal Carcinoma / 대한피부과학회지

Trichilemmal carcinoma is a rare adnexal tumor originating from outer root sheath of hair follicle. We report a case of trichilemmal carcinoma occurring on the scalp. A 71-year-old women presented with a nodule on the vertex of scalp. Histopathologically, tumor cells showed a lobular proliferation in continuity with the epidermis. The lobules showed peripheral palisading and trichilemmal keratinization. The prominent tumor cells were large cells with PAS-reactive, diastase-sensitive, clear cytoplasm. Striking cytologic atypia and high mitotic index were found. Total excision was done and the patient has been free of recurrence or metastasis for 1 year.

The Quality of Life of Acne Patients / 대한피부과학회지

Although acne is extremely prevalent, few studies have focused on the quality of life of the patient with acne vulgaris. Skin disease as acne are sometimes thought of as unimportant, even trivial, but acne vulgaris significantly affects patients' quality of life. This review describes the many ways in which skin disease can adversely affect the quality of life of patients with acne vulgaris.

The Quality of Life of Acne Patients / 대한피부과학회지

Although acne is extremely prevalent, few studies have focused on the quality of life of the patient with acne vulgaris. Skin disease as acne are sometimes thought of as unimportant, even trivial, but acne vulgaris significantly affects patients' quality of life. This review describes the many ways in which skin disease can adversely affect the quality of life of patients with acne vulgaris.

Treatment of Gingival Smile by Botulinum Toxin A / 대한피부과학회지

Gingival smile is a condition that causes a cosmetic problem by revealing excessive upper gingivae when one smiles. We, herein, report a case of a successfully treated gingival smile by injection of botulinum toxin A to levator labii superioris alaque nasi muscle.

A Sporadic Case of Punctate Palmoplantar Keratoderma / 대한피부과학회지

Punctate palmoplantar keratoderma(PPK) is a rare disease, characterized by small, hard hyperkeratotic papules which are irregularly distributed on the palms and soles. PPK is an autosomal dominant disease with variable penetrance. We report a case of sporadic case of punctate palmoplantar keratoderma in a 26-year-old female patient.